Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1893
Gene Symbol: ECM1
ECM1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human MiR-92a antagonized the facilitation effect of extracellular matrix protein 1 in GC metastasis through targeting its 3'UTR region. 31472228

2019

Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Long Noncoding RNA (lncRNA) MIR22HG Suppresses Gastric Cancer Progression through Attenuating NOTCH2 Signaling. 30670679

2019

Entrez Id: 84981
Gene Symbol: MIR22HG
MIR22HG
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Long Noncoding RNA (lncRNA) MIR22HG Suppresses Gastric Cancer Progression through Attenuating NOTCH2 Signaling. 30670679

2019

Entrez Id: 100128252
Gene Symbol: ZNF667-AS1
ZNF667-AS1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Epigenetic silencing of lncRNA MORT in 16 TCGA cancer types. 29707199

2018

Entrez Id: 9123
Gene Symbol: SLC16A3
SLC16A3
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis. 27224918

2016

Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer. 26719535

2016

Entrez Id: 100507056
Gene Symbol: CCAT1
CCAT1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer. 26752646

2016

Entrez Id: 1495
Gene Symbol: CTNNA1
CTNNA1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.340 GeneticVariation ORPHANET In HDGC families lacking CDH1 mutations, testing of CTNNA1 and other tumor suppressor genes should be considered. 26182300

2015

Entrez Id: 1495
Gene Symbol: CTNNA1
CTNNA1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.340 GeneticVariation ORPHANET Recognition of and recent issues in hereditary diffuse gastric cancer. 26049741

2015

Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Therapeutic CTD_human Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. 26401016

2015

Entrez Id: 4582
Gene Symbol: MUC1
MUC1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015

Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area. 25231345

2015

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide. 26558449

2015

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Therapeutic CTD_human Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. 26401016

2015

Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015

Entrez Id: 8000
Gene Symbol: PSCA
PSCA
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015

Entrez Id: 4316
Gene Symbol: MMP7
MMP7
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Association of MMP7 -181A→G Promoter Polymorphism with Gastric Cancer Risk: INFLUENCE OF NICOTINE IN DIFFERENTIAL ALLELE-SPECIFIC TRANSCRIPTION VIA INCREASED PHOSPHORYLATION OF cAMP-RESPONSE ELEMENT-BINDING PROTEIN (CREB). 25847246

2015

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population. 26384301

2015

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.360 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 9064
Gene Symbol: MAP3K6
MAP3K6
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.310 GermlineCausalMutation ORPHANET These findings, together with previous evidence from mouse models that MAP3K6 acts as a tumor suppressor, and studies showing the presence of somatic mutations in MAP3K6 in non-hereditary gastric cancers and gastric cancer cell lines, point towards MAP3K6 variants as a predisposing factor for FGC. 25340522

2014

Entrez Id: 1496
Gene Symbol: CTNNA2
CTNNA2
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 245972
Gene Symbol: ATP6V0D2
ATP6V0D2
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Expression of acidosis-dependent genes in human cancer nests. 25279216

2014

Entrez Id: 2737
Gene Symbol: GLI3
GLI3
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.300 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014